CONSIDERATIONS TO KNOW ABOUT LSD VIAL

Within the LSD-sure crystal structure, the facet chain in the lid residue L209EL2 forms extensive hydrophobic contacts with both LSD and encompassing residues in TMs III, IV, and V (Figure 4C). If the lid moved aside to show the binding pocket in simulation, a number of of these contacts broke. We thus hypothesized that L209EL2 functions to be a la